Table 1.
Effects of D. salina powder and extract on serum hepatic functions biomarkers.
| Normal control | TAA | Silymarin (50 mg/kg) | D. salina powder (12.5 mg/kg) | D. salina powder (25 mg/kg) | D. salina powder (50 mg/kg) | D. salina extract (12.5 mg/kg) | D. salina extract (25 mg/kg) | D. salina extract (50 mg/kg) | |
|---|---|---|---|---|---|---|---|---|---|
| ALT (U/L) | 43.82±0.37 | 68.52 ± 0.61a | 57.98 ± 0.17ab | 42.93 ± 0.33b | 40.17 ± 0.73b | 42.76 ± 0.45b | 38.81 ± 0.24b | 38.61 ± 0.27b | 38.81 ± 0.19b |
| ALT (% of TAA control) | (100 %) | 85 % | 63 % | 59 % | 62 % | 57 % | 56 % | 57 % | |
| AST (U/L) | 66.55 ± 0.08 | 103.3 ± 0.74a | 92.35 ± 0.41a | 88.18 ± 0.4ab | 88.03 ± 0.67ab | 87.51 ± 0.62ab | 95.18 ± 1.27a | 88.51 ± 0.54ab | 88.18 ± 0.81ab |
| AST (% of TAA control) | (100 %) | 89 % | 85 % | 85 % | 85 % | 92 % | 86 % | 85 % | |
| ALP (IU/L) | 57.85 ± 0.15 | 124.59 ± 0.48a | 115.38 ± 1.57a | 98.24 ± 0.59a | 69.56 ± 1.85b | 60.81 ± 0.77b | 93.82 ± 1.26a | 74.12 ± 1.79b | 67.21 ± 2.67b |
| ALP (% of TAA control) | (100 %) | 93 % | 79 % | 56 % | 49 % | 75 % | 59 % | 54 % | |
| Bilirubin (mg/dl) | 1.45 ± 0.01 | 2.62 ± 0.02a | 2.25 ± 0.01a | 2.15 ± 0.01a | 1.65 ± 0.04b | 1.53 ± 0.03b | 1.46 ± 0.01b | 1.30 ± 0.02b | 1.29 ± 0.00b |
| Bilirubin (% of TAA control) | (100 %) | 86 % | 82 % | 63 % | 59 % | 56 % | 50 % | 49 % | |
| Albumin (g/dl) | 4.19 ± 0.00 | 3.39 ± 0.03a | 3.43±0.02a | 3.54±0.02a | 3.86±0.02ab | 4.10±0.03b | 3.54±0.02a | 3.79±0.01ab | 3.81±0.03ab |
| (% of TAA control) | (100 %) | 101 % | 104 % | 114 % | 121 % | 104 % | 112 % | 112 % |