Table 4.

Comparison of the target genes found gained (A) or lost (B) in this and other studies, which are indicated through the bibliographic number: Wong et al. (8), Poorman et al. (24), Giannuzzi et al. (27), Hendricks et al. (28), Hayward et al. (6), Curtin et al. (5), Lyu et al. (7), and Furney et al. (4).

	Present study	CANINE studies				HUMAN studies
		Wong et al. (8)	Poorman et al. (24)	Giannuzzi et al. (27)	Hendricks et al. (28)	Wong et al. (8)	Poorman et al. (24)	Hayward et al. (6)	Curtin et al. (5)	Lyu et al. (7)	Furney et al. (4)
(A) GAINED GENES
MYC	V	V	V			V	V
KIT	V		V		V		V
PDGFRA	V							V
B2M*	V	V				V
BRAF						V	V	V
MDM2		V		V	V	V		V
CDK4		V			V		V	V	V	V
CCND1*		V	V			V	V	V	V
TRPM7	V		V	V
WIF1	V	V
SLC27A2	V			V
GABPB1	V			V
USP8	V			V
SPPL2A	V			V
CYP19A1	V			V
NOTCH1						V
SMO		V				V
TERT										V
(B) LOST GENES
BUB1B	V	V				V
KNSTRN	V	V				V
CYSLTR2	V	V				V
SPRED1	V		V	V		V
CDKN2A			V	V	V		V	V	V
PTEN			V				V	V	V
TP53								V			V
RB1	V	V	V
LCP1	V	V
FAM98B	V			V
PTPRJ		V				V
ARID1B						V

With ^* the genes B2M and CCND1: B2M was found gained in the present study, but was reported as lost by Wong et al. (8); CCND1 was reported as gained in hMMs, but lost in COMs, by Wong et al. (8) and Poorman et al. (24).