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pSTAT3 and RUNX1 expression in human kidneys with ADPKD. Representative immunohistochemistry of human kidneys. In healthy patients, the expression of pSTAT3 and RUNX1 was rarely detected (asterisks). In end-stage cystic kidneys from ADPKD patients, pSTAT3 and RUNX1 localised in the nuclei of the tubular epithelial cells (arrows) and infiltrating cells (arrowheads). Scale bars 100 μm
