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. 2019 Dec 12;12:293. doi: 10.3389/fnmol.2019.00293

FIGURE 2.

FIGURE 2

Identification of candidate lncRNA markers in relapsed DTCs. For this, we took relapsed samples indicated in GSE94035 to identify lncRNAs that are associated with tumor relapsing in neuroblastoma patients. Here we compared DELs in MNCs and DTCs of relapsed patients. (A–C) We found nine upregulated lncRNAs, AC004540.5, CASC15, CTD-2281E23.2, RFPL1S, RP11-134G8.8, LINC00511, PPP1R26-AS1, RP11-125B21.2, and RP11-544I20.2. Of these, the lncRNAs RP11-134G8.8, RP11-125B21.2, and RP11-544I20.2 were specifically differentially expressed only in relapsed DTCs. ∗∗∗p ≤ 0.0005, two-tailed unpaired t-test with Welch’s correction.