Table 1.
Association analysis between the expression level of RIZ1 and the clinicopathologic factors of FIGO stage I and II cervical cancer patients.
| Variables | N = 268 | RIZ1 Expression | P-valuea | |
|---|---|---|---|---|
| Negative (%) (n = 172) | Positive (%) (n = 96) | |||
| AGE (YEARS) | ||||
| <45 | 161 | 98 (57.0) | 63 (65.6) | 0.166 |
| ≥45 | 107 | 74 (43.0) | 33 (34.4) | |
| FIGO STAGE | ||||
| I | 115 | 63 (36.6) | 52 (54.2) | 0.005 |
| II | 153 | 109 (63.4) | 44 (45.8) | |
| HISTOLOGICAL TYPE | ||||
| SCC | 231 | 144 (83.7) | 87 (90.6) | 0.116 |
| AC | 37 | 28 (16.3) | 9 (9.4) | |
| HISTOLOGICAL GRADE | ||||
| G1 | 70 | 39 (22.7) | 31 (32.3) | 0.168 |
| G2 | 117 | 76 (44.2) | 41 (42.7) | |
| G3 | 81 | 57 (33.1) | 24 (25.0) | |
| TUMOR SIZE(CM) | ||||
| ≤4 | 190 | 118 (68.6) | 72 (75.0) | 0.269 |
| >4 | 78 | 54 (31.4) | 24 (25.0) | |
| DEEP STROMAL INVASION | ||||
| No | 91 | 46 (26.7) | 45 (46.9) | 0.001 |
| Yes | 177 | 126 (73.3) | 51 (53.1) | |
| LYMPHOVASCULAR SPACE INVOLVEMENT | ||||
| No | 189 | 114 (66.3) | 75 (78.1) | 0.041 |
| Yes | 79 | 58 (33.7) | 21 (21.9) | |
| PELVIC LYMPH NODE METASTASIS | ||||
| No | 187 | 110 (63.9) | 77 (80.2) | 0.005 |
| Yes | 81 | 62 (36.0) | 19 (19.8) | |
| POSTOPERATIVE RECURRENCE | ||||
| No | 169 | 97 (56.4) | 72 (75.0) | 0.002 |
| Yes | 99 | 75 (43.6) | 24 (25.0) | |
RIZ1, Retinoblastoma protein-interacting zinc-finger gene 1; FIGO, International Federation of Gynecology and Obstetrics; SCC, Squamous cell carcinoma; AC, Adenocarcinoma; Significant P < 0.05 are shown in bold.
a
χ2 test.