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. 2019 Dec 18;10:121. doi: 10.1186/s13244-019-0801-z

Table 1.

Treatment response features. Reprinted, with permission, from ACR [5]

Features Definitions
Viability Presence of live tumor cells within or along the margin of a treated lesion. Radiologic viability is not synonymous with pathologic viability as imaging is not sensitive to microscopic or small foci of residual tumor.

Treatment-specific expected enhancement

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Expected temporal and spatial pattern of posttreatment enhancement attributable to treatment-related changes in parenchymal perfusion.

Posttreatment enhancement patterns may not reliably differentiate viable from nonviable tumor. The most appropriate response category may be LR-TR Equivocal.

No lesional enhancement

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Absence of enhancement within or along the margin of a treated lesion.

Note: complete disappearance after locoregional treatment is considered equivalent to absence of enhancement.

Posttreatment APHE

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Nodular, masslike, or thick and irregular arterial phase hyperenhancement (APHE) contained within or along the margin of a treated lesion suggests posttreatment tumor viability.

Posttreatment “washout”

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Nodular, masslike, or thick and irregular washout appearance contained within or along the margin of a treated lesion suggests posttreatment tumor viability.

Posttreatment enhancement similar to pretreatment

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Nodular, masslike, or thick and irregular enhancement similar to pretreatment enhancement in all postcontrast phases contained within or along the margin of a treated lesion suggests posttreatment tumor viability, even in the absence of APHE or washout appearance.