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. 2019 Nov 16;31:138–149. doi: 10.1016/j.molmet.2019.10.008

Figure 7.

Figure 7

Deficiency of FPR2 impaired leukocyte phenotypes post-MI. Flow cytometry (FACs) pseudo plots representing monocyte populations (CD45+/CD11b+) in WT and FPR2−/− mice at post-MI d1: (A) spleen-CD11b+, (B) LV-CD11b+ population. (C) Histogram displaying CD11b+ expression of spleen and LV. (D) Percentage of CD11b+ population in spleen and LV. (E) Splenic neutrophils (CD45+/CD11b+/F4/80-/Ly6G+). (F) LV-Ly6G+. (G) Histograms representing Ly6G+ expression of spleen and LV. (H) Percentage of Ly6G+ population in spleen and LV. Flow cytometry (FACs) pseudo plots representing macrophage populations (CD45+/CD11b+/F4/80+) in WT and FPR2−/−: (I) splenic macrophages (F4/80+) and (J) LV macrophages (F4/80+) post-MI. (K) Histograms representing F4/80+ expression in WT and FPR2−/− spleen and LV. (L) Percentage of Ly6G+ population in the spleen and LV. (M) Splenic macrophage subpopulations (F4/80+/Ly6Clow/high). (N) LV macrophage subpopulations (F4/80+/Ly6Clow/high). (O) Histograms displaying Ly6Clow/high expression of the spleen and LV. (P) Percentage of Ly6Clow population in the spleen and LV. *p < 0.05 vs WT. Values are means ± SEM; n = 4 mice/group.