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. 2019 Dec 18;9:19377. doi: 10.1038/s41598-019-55848-7

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of Na₂S₄ on voltage-dependent outward potassium currents in mouse MIN6 cells. (a) Current–voltage relationships of whole-cell currents with varying concentrations of Na₂S₄ (in 0, 5, 25, 50, or 500 μM). Na₂S₄ increased inwardly rectifying potassium currents in a dose-dependent manner (n = 5). (b) Semi-logarithmic plot of the conductance between −108 and −68 mV by concentration of Na₂S₄ with the standard K⁺ pipette solution included ATP at 0.01 mM (closed circles) and 1 mM (open circles).