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. 2019 Dec 18;9:19350. doi: 10.1038/s41598-019-55521-z

Figure 3.

Figure 3

Effect of TLR4 blockade on CD4+ T lymphocytes in model of adoptive transfer of diabetes. (A) expression of CD25 on BDC2.5 CD4+ T cells in pancreatic lymph nodes (PLN) and spleen. (B) Cytokine secretion measured in sera of treated and control animals. (C,D) %IFNγ- and IL-17A-producing BDC2.5 CD4+ T cells in PLN and spleen. (E,F) quantification of the production IFNγ of IL-17A in PLN and spleen. Data are means ± SEM collected from four mice *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001