Figure 6.

Microbiome profiles of each disease group with and without antibiotics (Abx). The relative proportion of the bacterial taxa identified from the lungs at the phylum level by 16S sequencing for the respective infection groups both with and without antibiotic pre-treatment (A). Principle component analysis of the microbial taxa in the Abx-treated mice with influenza-pneumococcal infection or the triple morbidity infection model showing clustering of microbiome for the study groups (B). The cladogram for the enriched taxa with and without antibiotic treatment for influenza-pneumococcal co-infection and the impact of allergic asthma on these relative abundances (cutoff is lda >3) (C).