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. 2019 Dec 18;9:19402. doi: 10.1038/s41598-019-55294-5

Figure 2.

Figure 2

BDNF quantification confirming successful increase in BDNF in the targeted ipsilateral side. Total BDNF protein concentration per mg of total protein in the (A) striatum and (B) substantia nigra dissected from WT mice IN+FUS BDNF (n = 3). (C) Axial T1-weighted contrasted enhanced MRI showing examples of with poor and good targeting within the striatum (outlined by dotted red lines). Cases with poor targeting were excluded from the statistical analysis. (D) Experimental timeline for the short-term study to quantify BDNF delivery.