Table 2.
Significantly prolonged average optical path length delay Δφ and refractive index (RI) in stenotic compared to non-stenotic intestinal tissue of Crohn’s disease patients (surgical resection specimen n = 30; number of patients = 15).
| Non-stenotic tissue (n = 15) | Stenotic tissue (n = 15) | ||||
|---|---|---|---|---|---|
| Δφ (rad) | RI | Δφ (rad) | RI | P value | |
| Overall | 1.544 ± 0.034 | 1.356 ± 0.000 | 1.802 ± 0.045 | 1.359 ± 0.001 | <0.001*** |
| Mucosa | 1.434 ± 0.044 | 1.354 ± 0.001 | 1.445 ± 0.035 | 1.354 ± 0.000 | 0.833 |
| Submucosa | 1.743 ± 0.080 | 1.358 ± 0.001 | 2.228 ± 0.072 | 1.364 ± 0.001 | <0.001*** |
| Muscularis | 1.571 ± 0.050 | 1.356 ± 0.001 | 1.678 ± 0.043 | 1.357 ± 0.001 | 0.337 |
Arithmetic mean and standard error of mean (SEM) are reported for continuous variables. Statistical analysis was performed using Mann-Whitney U test. Two-sided p values < 0.05 were considered statistically significant.