Table 5.

α,β,γ - mangostin attenuates oxidative stress and inflammation interacting with IP₃R, KEAP-1, p38 kinase, JNK and NF-kB.

Compound names	IP3R (PDB:3UJ0)			KEAP-1 (PDB:5CGJ)			p38 kinase (PDB:2YIS)			JNK (PDB:3OY1)			NF-kB (PDB:4KIK)
	Docking score	Glide e model	Glide energy	Docking score	Glide e model	Glide energy	Docking score	Glide e model	Glide energy	Docking score	Glide e model	Glide energy	Docking score	Glide e model	Glide energy
α -mangostin	−3.357	−45.267	−37.929	−5.63	−61.434	−44.618	−4.569	−41.359	−40.702	−6.707	−67.529	−48.892	−7.187	−68.143	−48.554
β -mangostin	−3.171	−44.084	−37.195	−4.616	−55.464	−43.602	−4.149	−49.645	−41.21	−6.535	−67.363	−50.166	−6.606	−68.279	−51.382
γ -mangostin	−3.38	−45.657	−38.001	−4.917	−56.047	−43.873	−5.004	−45.676	−38.879	−6.941	−71.599	−50.986	−7.183	−72.28	−51.774