Figure 3.
[89Zr]A2cDb immunoPET of hPSCA Ki mice. a In vivo [89Zr]A2cDb immunoPET (2–2.8 MBq/12–15 μg, i.v. tail vein) at 5 and 20 h post injection into hPSCA KI mice (n = 6) and C57BL/6J wild type mice (n = 4). Scans are displayed as whole-body MIP/CT overlays. b Ex vivo PET/CT scans of normal PSCA-expressing tissues. hPSCA KI mice (left panels) showed slightly higher tracer uptake in the stomach compared with C57BL/6J wild type mice.