Figure 6: Norepinephrine treatment does not induce ER stress in mesenchymal primary human fibroblast cells.
A-C) Isolated fibroblasts from human skin were treated for 24 hours with 100 μM norepinephrine and immunostaining of (A) BiP, (B) ATF6, and (C) PERK were performed and quantified respectively. D) Adrenoceptors α1A, α1B, α1D, α2A, α2B, α2C, β1, β2, β3 expression in human fibroblasts were assessed as described in (A-C). Experiments were repeated 3 separate times with a total sample size (n=5–9) per group included in the analysis.
