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. 2019 Dec 14;25(46):6728–6742. doi: 10.3748/wjg.v25.i46.6728

Figure 5.

Figure 5

Effects of inhibiting the expression of HULC on the Wnt/β-catenin signaling pathway. A: The expression of β-catenin, c-myc, and cyclin D1 proteins in BxPC3 cells after transfection; B: The expression of β-catenin, c-myc, and cyclin D1 proteins in PANC-1 cells after transfection; C: Proliferation of BxPC3 cells with HULC expression inhibited by LiCl; D: Proliferation of PANC-1 cells with HULC expression inhibited by LiCl; E: Apoptosis of BxPC3 and PANC-1 cells with HULC expression inhibited by LiCl; F: Invasion of BxPC3 and PANC-1 cells with HULC expression inhibited by LiCl; G: The expression of β-catenin, c-myc, and cyclin D1 proteins in BxPC3 cells with HULC expression inhibited by LiCl; H: The expression of β-catenin, c-myc, and cyclin D1 proteins in PANC-1 cells with HULC expression inhibited by LiCl; I: Protein band; J: Cell invasion; K: Cell apoptosis. aP < 0.05, bP < 0.01 for between-group comparisons.