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The particle size distribution (A) of about 100 nm diameters (represented small particle size) by nanoprecipitation method (a); of about 260 nm diameters (represented medium particle size) by an emulsification/solvent evaporation approach (b); of about 600 nm diameters (represented large particle size) by an emulsification/solvent evaporation approach (c); and TEM morphology (B) of PLGA nanoparticles.
