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. 2017 Oct 11;24(1):1549–1564. doi: 10.1080/10717544.2017.1386729

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© 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Cellular uptake of GE11-Se NPs. Cellular uptake of (A) coumarin-6-loaded GE11-Se NPs and (B) coumarin-6-loaded Chi-Se NPs in KYSE-150 cells, n = 3. Cellular uptake of coumarin-6-loaded GE11-Se NPs in (C) FLS and (D) THP-1 cells, n = 3. (E) EGFR expression in KYSE-150 cells, fibroblast-like synovial cells and THP-1 cells. (F) Intracellular uptake of coumarin-6-loaded GE11-Se NPs in KYSE-150 cells with free GE11 peptide competition, n = 3. (G) Cellular uptake of coumarin-6-loaded GE11-Se NPs in KYSE-150 cells with anti-EGFR antibody block, n = 3. (H) Cellular uptake of coumarin-6-loaded GE11-Se NPs in KYSE-150 cells under different endocytosis inhibition conditions, n = 3.