Table 1.
The ingredients of DS liposomal formulations.
| Ingredients | DSPE-PEG2000 | HSPC | DPPC | Ch | DS | |
|---|---|---|---|---|---|---|
| Formulation | ||||||
| HSPC:Ch | 0.0 (mol% *) | - | 1 ** | - | 1 | - |
| 5.0 | - | 1 | - | 1 | 0.11 | |
| 10.0 | - | 1 | - | 1 | 0.22 | |
| 15.0 | - | 1 | - | 1 | 0.36 | |
| PEG:HSPC:Ch | 0.0 | 0.1 | 0.9 | - | 1 | - |
| 5.0 | 0.1 | 0.9 | - | 1 | 0.11 | |
| 10.0 | 0.1 | 0.9 | - | 1 | 0.22 | |
| 15.0 | 0.1 | 0.9 | - | 1 | 0.36 | |
| DPPC:Ch | 0.0 | - | - | 1 | 1 | - |
| 5.0 | - | - | 1 | 1 | 0.11 | |
| 10.0 | - | - | 1 | 1 | 0.22 | |
| 15.0 | - | - | 1 | 1 | 0.36 | |
| PEG:DPPC:Ch | 0.0 | 0.1 | - | 0.9 | 1 | - |
| 5.0 | 0.1 | - | 0.9 | 1 | 0.11 | |
| 10.0 | 0.1 | - | 0.9 | 1 | 0.22 | |
| 15.0 | 0.1 | - | 0.9 | 1 | 0.36 |
* Drug lipid molar percentage. ** Molar ratio.