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PMN phagocytosis of S. aureus is promoted by surfactant protein D (SP-D), and S. aureus cysteine protease diminished SP-D activity. (A) PMNs shown are from tear fluid after inoculation with S. aureus or S. aureus with E64 (cysteine protease inhibitor). (B) Phagocytic index (PI) from PMNs in the tear fluid of infected wild-type (WT) and SP-D KO mice. #, PMNs; Arrows, S. aureus. This figure is reproduced under a Creative Commons License from © 2015 PLoS ONE [99].
