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. 2019 Nov 18;9(11):746. doi: 10.3390/biom9110746

Figure 1.

Figure 1

Concentration-dependent effects of local administration of MK801 (0, 1 and 5 μM) into the mPFC on extracellular levels of l-glutamate (A), GABA (B), serotonin (C), norepinephrine (D), and dopamine (E) in the mPFC (Study_1). Ordinates: mean ± SD (n = 6) of extracellular transmitter levels (μM or nM); abscissa: time after MK801 administration (min). Light blue and gray bars indicate perfusion with muscimol (Mus) and MK801 into the mPFC, respectively. * p < 0.05, ** p < 0.01; relative to control or 5 μM MK801 by multivariate analysis of variance (MANOVA) with Tukey’s post hoc test.