Table 6.
Serum levels of IL-6, IL-12, TNF-α, and IFN-γ in mice (N = 10).
| Group | IL-6 (pg/mL) |
IL-12 (pg/mL) |
TNF-α (pg/mL) |
IFN-γ (pg/mL) |
|---|---|---|---|---|
| Normal | 36.77 ± 3.45 e | 205.67 ± 16.27 e | 22.34 ± 3.06 e | 19.87 ± 2.36 e |
| Model | 221.80 ± 18.92 a | 805.62 ± 31.20 a | 92.54 ± 5.28 a | 80.11 ± 4.62 a |
| Silymarin | 75.36 ± 5.30 d | 415.28 ± 14.69 d | 48.36 ± 3.62 d | 32.58 ± 2.87 d |
| LP-HFY05-L | 128.75 ± 11.03 c | 581.24 ± 25.33 c | 68.20 ± 3.74 c | 46.67 ± 3.56 c |
| LP-HFY05-H | 71.39 ± 4.92 d | 401.87 ± 18.31 d | 44.58 ± 4.02 d | 29.87 ± 3.12 d |
| LDSB | 178.45 ± 15.27 b | 677.80 ± 22.36 b | 80.52 ± 3.68 b | 61.02 ± 4.02 b |
Values mean ± standard deviation (N = 10/group). Sample data in each group come from a normal distribution. The difference in variance between the two groups was significant (p < 0.05). a–e Mean values with different letters over the same column are significantly different (p < 0.05) according to Tukey’s honestly significant difference test. Silymarin: Mice treated with silymarin (100 mg/kg), LP-HFY05-L: Mice treated with a low concentration of Lactobacillus plantarum HFY05 (1.0 × 108 CFU/kg), LP-HFY05-H: Mice treated with a high concentration of Lactobacillus plantarum HFY05 (1.0 × 109 CFU/kg), LDSB: Mice treated with Lactobacillus delbrueckii subsp. bulgaricus (1.0 × 109 CFU/kg). IL-6, interluekin-6; TNF-α, tumor necrosis factor-alpha; IFN-γ; interferon-gamma.