Table 7.
Intestinal fecal microbiota of mice in each group (N = 10, 16 rRNA gene copy number, log10/g).
| Group | Normal | Model | Silymarin | LP-HFY05-L | LP-HFY05-H | LDSB |
|---|---|---|---|---|---|---|
| Firmicutes | 6.35 ± 0.31 e | 8.52 ± 0.47 a | 8.12 ± 0.28 b | 7.64 ± 0.31 c | 7.01 ± 0.21 d | 8.05 ± 0.23 b |
| Bacteroides | 11.39 ± 0.42 a | 7.91 ± 0.35 e | 8.26 ± 0.28 d | 8.77 ± 0.22 c | 9.40 ± 0.42 b | 8.23 ± 0.20 d |
| Actinobacteria | 1.21 ± 0.15 f | 4.32 ± 0.18 a | 3.89 ± 0.12 b | 2.34 ± 0.11 d | 1.81 ± 0.17 e | 2.97 ± 0.13 c |
| Proteobacteria | 2.36 ± 0.17 f | 5.92 ± 0.20 a | 4.98 ± 0.18 b | 3.69 ± 0.21 d | 2.91 ± 0.30 e | 4.02 ± 0.19 c |
| Bifidobacterium | 2.26 ± 0.11 a | 0.35 ± 0.04 d | 0.42 ± 0.05 d | 0.82 ± 0.08 c | 1.89 ± 0.15 b | 0.78 ± 0.09 c |
| Lactobacillus | 5.23 ± 0.21 c | 2.15 ± 0.16 e | 2.87 ± 0.19 d | 9.41 ± 0.22 b | 14.83 ± 0.24 a | 4.92 ± 0.24 c |
| Enterobacteriaceae | 2.30 ± 0.21 e | 6.98 ± 0.31 a | 6.34 ± 0.28 b | 5.23 ± 0.20 d | 2.42 ± 0.25 e | 5.51 ± 0.18 c |
Values are mean ± standard deviation (N = 10/group). Sample data in each group come from a normal distribution. The difference in variance between the two groups was significant (p < 0.05). a–f Mean values with different letters over the same row are significantly different (p < 0.05) according to Tukey’s honestly significantly different test. Silymarin: Mice treated with silymarin (100 mg/kg), LP-HFY05-L: Mice treated with a low concentration of Lactobacillus plantarum HFY05 (1.0 × 108 CFU/kg), LP-HFY05-H: Mice treated with a high concentration of Lactobacillus plantarum HFY05 (1.0 × 109 CFU/kg), LDSB: Mice treated with Lactobacillus delbrueckii subsp. bulgaricus (1.0 × 109 CFU/kg).