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. 2019 Oct 28;11(11):559. doi: 10.3390/pharmaceutics11110559

Figure 1.

Figure 1

Preliminary characterization of liposomal formulations during development and optimization. (A) Cryo TEM micrographs of metformin hydrochloride (Met) ND lipo. Scale bar = 200 nm. (B) Cryo TEM images of Met DO lipo. Scale bar = 200 nm. (C) In Vitro drug release profile of optimized formulation, Met ND lipo, and Met DO lipo as revealing all the drug being released with 6 h. Data represent mean ± SD (n = 3).