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. 2019 Nov 17;11(11):616. doi: 10.3390/pharmaceutics11110616

Table 2.

Critical formulation temperatures. Glass transition temperature (Tg’) and onset of collapse temperature (Tc) of the liquid formulations.

Formulation mAb Concentration(mg/mL) Tg’ (°C) Tc (°C)
FS 10 −29.5 −31.0
50 −25.4 −20.4
FCD 10 −10.9 −10.1
50 −8.3 −6.3
FCD/P/S 10 −19.2 −18.5
50 −16.5 −14.6
FCD/S 10 −18.6 −16.0
50 −15.2 −10.9