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Optimized Lira loaded PLGA NPs; where PVA is the polyvinyl alcohol-stabilizer, and W2/O is the outer aqueous phase to organic phase ratio.
| Formulation Parameters | |
|---|---|
| PLGA amount | 60 mg |
| Lira amount | 5 mg |
| 2nd sonication time | 0.5 min |
| PVA amount | 1.48% |
| Lyoprotectant type | Mannitol |
| Lyoprotectant amount | 5% |
| W2/O ratio | 5 |
