Table 1.

Post-translational modifications of PTEN.

Modification	Modifier	Site
phosphorylation	CK2 [121,122,123]	S370, S385 [121,122,123]
	GSK3β [124]	T366 [124]
		T382, T383 [125] S380, T382, T383 [126] S380, T382, T383, T385 [127,128]
	FGFR,SRC family kinases [129] FGFR2 [130]	Y240 [130,131]
Ubiquitination	Need4-1 [129,132,133] CHIP [134] NRF146 [135] WWP2 [136,137] WWP1 [138,139] XIAP [140]	K13, K289 K48 [134]     K27 [139]
Oxidation	ROS [141,142] Thioreductase [142]	C71, C124 [141,142]
Acetylation	PCAF [143]	K125, K128 [143]
	CBP [144]	K402 [144]
	HDAC6 [145]	K163 [145]
S-nitrosylation	NO [146]	C83 [146]
Ribosylation	TNKS1, TNKS2 [135]
Sumoylation	SUMO1 [147]	K266 [147]