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. 2019 Nov 13;15:248–260. doi: 10.1016/j.omto.2019.10.008

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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miR-424-5p Does Not Affect Growth and Proliferation of Thyroid Cancer Cells

The effects of miR-424-5p on proliferation rate in the indicated B-CPAP (A and B) and K1 (C and D) cells via CCK-8 assay. Each bar represents the mean values ± SD of three independent experiments. (E) The effects of miR-424-5p on colony formation ability in the indicated thyroid cancer cells via colony formation assay. Each bar represents the mean values ± SD of three independent experiments. (F) Flow cytometric analysis of the effects of miR-424-5p on cell cycle in the indicated thyroid cancer cells. Each bar represents the mean values ± SD of three independent experiments. (G) Images of excised tumors from the mice at 35 days after injection with the indicated cells. (H) Tumor volumes were measured every 5 days. Each bar represents the median values ± quartile values. (I) Average weight of excised tumors from the indicated mice. Each bar represents the median values ± quartile values. (J) The effects of miR-424-5p on anchorage-independent ability in the indicated thyroid cancer cells via anchorage-independent growth assay. Each bar represents the mean values ± SD of three independent experiments. *p < 0.05.