Fig. 3.
The effect of 5 weeks daily treatment with atorvastatin (50 mg/kg) and rutin (100 mg/kg) on the relaxation response of the aorta induced by cumulative application of acetylcholine. Rutin and atorvastatin improved the relaxation response at a concentration of 3 × 10−7 mol/l of acetylcholine. The rats were divided into three groups: HTG-HFFD – hypetriacylglycerolemic rats fed with high-fat-high-fructose diet (HFFD), HTG-HFFD-A – hypertriacylglycerolemic rats fed with HFFD receiving atorvastatin, HTG-HFFD-R – hypertriacylglycerolemic rats fed with HFFD treated with rutin, n = 10 rats/group. Data are expressed as means ± SEM. *p < 0.05 HTG-HFFD vs HTG-HFFD-A, #p < 0.05 HTG-HFFD vs HTG-HFFD-R.