Table 2.
Neuropathy | ||
Focal neuropathies | Increased CSA, hypoechoic proximal to site of entrapment, decreased nerve mobility, increased intraneural vascularity | |
Normal CSA cutoffs: | ||
Median nerve at wrist | ≤10 mm2 ;or WFR of 1.4 (Fowler et al., 2014, Mhoon et al., 2012) | |
Ulnar nerve at elbow | ≤10 mm2 (Beekman et al., 2011) | |
Radial nerve at spiral groove | ≤10 mm2 (Cartwright et al., 2008) | |
Fibular nerve at fibular head | ≤12 mm2 (Cartwright et al., 2008) | |
Tibial nerve in tarsal tunnel | ≤19 mm2 for CSA within the tunnel; or within tunnel-to-proximal tunnel CSA ratio 1.0 (Tawfik et al., 2016) | |
Hereditary neuropathies (e.g. CMT1a) | Diffuse nerve enlargement and prominent dark fascicles | |
Acquired inflammatory polyneuropathies (e.g. CIDP) | Multifocal nerve enlargement outside of areas of compression | |
Myopathy | ||
Muscular dystrophy | Hyperechoic muscle with attenuation of the underlying bone | |
Inflammatory myopathy | Although likely dependent on chronicity, the most common findings are hyperechoic muscle, normal underlying bone echo, possibly increased muscle thickness, and increased vascularity. | |
Motor neuron disease | ||
Hyperechoic muscle with decreased thickness, decreased muscle echovariation; presence of fasciculations; reduction in cervical root and peripheral nerve CSA |
CSA: Cross-sectional area; WFR: Wrist-to-forearm ratio; CMT1a: Charcot-Marie-Tooth type 1a; CIDP: Chronic inflammatory demyelinating polyneuropathy.