Table 1.
Clinical features of patients with autoimmune thyroid disease (AITD) from whom NGS was performed.
| AITD | HT | GD | GO | p-value |
|---|---|---|---|---|
| n | 5 | 4 | 5 | |
| Gender (F/M) | 5/0 | 4/0 | 5/0 | |
| Age (year) | 54.2 ± 12.3 | 47.2 ± 15.4 | 40.6 ± 11.6 | 0.3024 (one way ANOVA) |
| TSH mU/mL | 1.7 (1.04–15.22) | 2.8 (0.48–7.6) | 2.5 (0.5–21.72) | 0.9463 (Kruskal–Wallis test) |
| T4 ng/dL | 1.1 (1.1–1.12) | 0.86 (0.81–1.5) | 1.19 (0.67–1.27) | 0.9452 (Kruskal–Wallis test) |
| Tg-Ab UI/mL | 342 (133.8–446.8) | – | – | – |
| TPO-Ab UI/mL | 228 (52.5–1577) | – | – | – |
| TSHR-Ab U/L | – | 3.655 (1.46–23.05) | 4.37 (1.55–16.63) | > 0.9999 (Mann–Whitney test) |
Values show number for categorical values and median (interquartile intervals 25–75) for continuous variables. HT = Hashimoto's thyroiditis; GD = Graves’ disease. F/M = female/male; TSH, thyrotropin (Normal range = 0.27–4.20); T4, thyroxine (Normal range = 0.93–1.7); Tg-Ab, anti-thyroglobulin antibody (Negative <344); TPO-Ab, anti-thyroid peroxidase antibody (Negative <100); TSHR-Ab, anti-thyrotropin receptor antibody (Negative <0.7).