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Schematic overview of the study. Patients received three vaccinations (red arrows) before the season of each treatment year (1 and 2) and one booster vaccination in October of treatment year 1. Grass pollen counts (y-axes, grey bars, grains per m3 per day) are shown for year 1 (upper graph) and year 2 (lower graph). Time points for blood collection are shown by black arrows.
