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. 2019 Dec 11;37(1):14–26. doi: 10.1089/neu.2019.6422

FIG. 2.

FIG. 2.

Presence of mCherry-labeled MSCs in the ipsilateral brain hemisphere. (A) Schematic illustration of the location of the detected mCherry-labeled MSCs in the ipsilateral brain hemisphere. Representative images of mCherry immunereactivity in coronal sections of ipsilateral hemisphere of injured brains at 28 days post-injury showing the presence and selectivity of MSC-mCherry (B) and MSC-FGF21 (C) after MSCs were injected into the contralateral lateral ventricle. MSC-mCherry and MSC-FGF21 cells were stably overexpressing the mCherry protein and used as cellular label to localize the transplanted MSCs. MSC-mCherry and MSC-FGF21 were located mainly in the ipsilateral cortex and hippocampus (dashed boxes). Scale bar, 100 μm, unless stated otherwise. FGF21, fibroblast growth factor 21; MSCs, mesenchymal stem cells; TBI, traumatic brain injury.