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. 2019 Sep 26;15(3):473–481. doi: 10.4103/1673-5374.266059

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Copyright: © Neural Regeneration Research

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LIG reduces the OGD/R-induced inhibition of PC12 cell proliferative activity.

The four experimental groups included control, LIG, 3-MA and LIG + 3-MA groups. The cells were subjected to OGD/R for 0, 3, 12 or 24 hours. Data are expressed as the mean ± SD. #P < 0.05, ##P < 0.01, vs. LIG group (one-way analysis of variance followed by Dunnett’s test). Experiments were repeated at least three times. 3-MA: 3-Methyladenine; LIG: ligustilide; MTS: 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium; OD: optical density; OGD/R: oxygen-glucose deprivation/reoxygenation.