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Comparison of scSplit and demuxlet performance in demultiplexing merged three individually genotyped stromal samples (TPR true positive rate, FDR false discovery rate); Total cell numbers: 9567; Reads per cell: 14,495; Informative SNVs: 63,129; Runtime for matrices building: 67 min, Runtime for cell assignment: 55 min
| Predictions vs Truth | TPR | FDR | Cohen’s Kappa | |
|---|---|---|---|---|
| scSplit | Singlet | 0.94 | 0.02 | 0.95 |
| Doublet | 0.65 | 0.04 | ||
| demuxlet | Singlet | 0.93 | 0.02 | 0.77 |
| Doublet | 0.66 | 0.47 | ||
