Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Comparison of scSplit and demuxlet performance in demultiplexing hashtagged and multiplexed eight individually genotyped PBMC samples (TPR true positive rate, FDR false discovery rate); total cell numbers: 7932; reads per cell: 5835; informative SNVs: 16,058; runtime for matrices building: 35 min, runtime for cell assignment: 20 min
| Predictions vs Truth | TPR | FDR | Cohen’s Kappa | |
|---|---|---|---|---|
| scSplit | Singlet | 0.98 | 0.13 | 0.75 |
| Doublet | 0.35 | 0.28 | ||
| demuxlet | Singlet | 0.79 | 0.10 | 0.74 |
| Doublet | 0.65 | 0.46 | ||
