FIG 2.

Pathological changes in the spleens and livers of infected C57BL/6J and CC042 mice. The images show C57BL/6J and CC042 mouse spleen sections stained with hematoxylin and eosin at day 0 after Salmonella infection (A) and spleen and liver sections stained with hematoxylin and eosin at day 3 after Salmonella infection (B) and are representative of those for 6 C57BL/6J mice and 6 CC042 mice. Foci of necrotic hepatocytes associated with histiocytes and neutrophils were seen in both C57BL/6J and CC042 mice but were smaller and less numerous in the CC042 mouse samples (2 to 4 foci per ×40-magnification field of view in CC042 mice compared to 4 to 5 foci in C57BL/6J mice). Arrows point to inflammatory foci. WP, white pulp; RP, red pulp.