FIG 6.

Egr-1-deficient BMDCs have increased LIX production following P. aeruginosa infection. Wild-type (+/+) and Egr-1-deficient (−/−) BMDCs were infected with P. aeruginosa strain 8821 at an MOI of 10 for 3 h, 6 h, or 12 h or were left untreated (NT). Cell supernatants were collected for the determination of IL-1β (A), IL-6 (B), TNF (C), IL-12 (D), IL-17 (E), MIP2 (F), KC (G), LIX (H), IP-10 (I), and RANTES (J) secretion by ELISA (n = 3 ± SEM; *, P < 0.05; **, P < 0.01; ****, P < 0.0001; N.D., not detected).