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. 2019 Dec 12;10:2810. doi: 10.3389/fmicb.2019.02810

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Copyright © 2019 Gong, Shi, Bai, He, Zhang, Li, Wan, Lin, Qiu, Chen, Hu and Cao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Diarrhea induced by Proteus mirabilis C02011 was observed in BALB/c mice. (A) Streptomycin-treated mice were gavaged with P. mirabilis C02011, P. mirabilis B02005, and normal saline. Clinical symptoms and colonic lesions were evaluated by indicators. (B) Feces images of mice in different groups. (C) Feces water content of mice in different groups was recorded at 0, 1, 3, and 5 h after infection. (D) Colon images in different groups. (E) Anal region images of mice in different groups. (F) Mouse colon length was measured in different groups. (G) The level of TNF-α in colon tissues. ^∗P < 0.05, ^∗∗P < 0.01.