TABLE 1.
Baseline Characteristics
| Overall (N ¼ 14,171) |
Patients With PCI (n ¼ 153) |
Patients Without PCI (n = 14,018) |
p Value | |
|---|---|---|---|---|
| Age, yrs | 73 (65, 78) | 73 (67, 79) | 73 (65, 78) | 0.305 |
| Female | 5,605 (39.6) | 27 (17.6) | 5,578 (39.8) | <0.001 |
| BMI, kg/m2 | 28.2 (25.1, 32.0) | 28.9 (26.0, 32.4) | 28.2 (25.1, 32.00 | 0.105 |
| SBP, mm Hg | 130 (120, 140) | 130 (120, 140) | 130 (120, 140) | 0.039 |
| DBP, mm Hg | 80 (70, 85) | 80 (70, 82) | 80 (70, 85) | 0.024 |
| Type of AF | 0.247 | |||
| Persistent | 11,485 (81.1) | 116 (75.8) | 11,369 (81.1) | |
| Paroxysmal | 2,490 (17.6) | 34 (22.2) | 2,456 (17.5) | |
| Newly diagnosed | 196 (1.4) | 3 (2.0) | 193 (1.4) | |
| Previous medication use | ||||
| Aspirin | 5,184 (36.6) | 65 (42.5) | 5,119 (36.5) | 0.128 |
| VKA | 8,853 (62.3) | 113 (73.9) | 8,740 (62.3) | 0.004 |
| CHADS2 score | 3.5 _ 0.9 | 3.5 _ 1.0 | 3.5 _ 0.9 | 0.928 |
| CHADS2 score | ||||
| 1 | 3 (0.0) | 0 (0.0) | 3 (0.0) | |
| 2 | 1,857 (13.1) | 25 (16.3) | 1,832 (13.1) | |
| 3 | 6,169 (43.5) | 60 (39.2) | 6,109 (43.6) | |
| 4 | 4,067 (28.7) | 40 (26.1) | 4,027 (28.7) | |
| 5 | 1,797 (12.7) | 26 (17.0) | 1,771 (12.6) | |
| 6 | 278 (2.0) | 2 (1.3) | 276 (2.0) | |
| Coexisting condition | ||||
| Prior stroke/TIA/non-CNS embolism |
7,767 (54.8) | 86 (56.2) | 7,681 (54.8) | 0.726 |
| Congestive HF | 8,851 (62.5) | 82 (53.6) | 8,769 (62.6) | 0.023 |
| Hypertension | 12,824 (90.1) | 132 (86.3) | 12,692 (90.5) | 0.074 |
| Diabetes | 5,647 (39.9) | 75 (49.0) | 5,572 (39.7) | 0.020 |
| Prior MI | 2,446 (17.3) | 50 (32.7) | 2,396 (17.1) | <.001 |
| PAD | 832 (5.9) | 18 (11.8) | 814 (5.8) | 0.002 |
| COPD | 1,481 (10.5) | 17 (11.1) | 1,464 (10.4) | 0.790 |
| CrCl, ml/min* | 67 (52, 87) | 71 (53, 88) | 67 (52, 87) | 0.483 |
Values are median (25th, 75th percentile), n (%), or mean _ SD.
Creatinine clearance was calculated using the Cockcroft-Gault equation.
AF ¼ atrial fibrillation; BMI ¼ body mass index; CHADS2 ¼ Congestive Heart Failure, Hypertension, Age $75 Years, Diabetes Mellitus [1 point for presence of each], and Stroke/TIA [2 points]; scores range from 0 to 6; CNS ¼ central nervous system; COPD ¼ chronic obstructive pulmonary disease; CrCl ¼ creatinine clearance; DBP ¼ diastolic blood pressure; HF ¼ heart failure; MI ¼ myocardial infarction; PAD ¼ peripheral artery disease; PCI ¼ percutaneous coronary intervention; SBP ¼ systolic blood pressure; SD ¼ standard deviation; TIA ¼ transient ischemic attack; VKA ¼ vitamin K antagonist.