Table 2.
Laboratory values according to time point and platelet transfusion.
Laboratory test | Time point | No platelet transfusion | Platelet transfusion | ||
---|---|---|---|---|---|
Median (IQR) | P-value | Median (IQR) | P-value | ||
TEG-PM ADP MA (mm) | Pre-operative | 43.8 (33.1, 55.2) | <0.005 | 17.5 (9.7, 42.0) | 0.6 |
Intra-operative | 13.4 (7.5, 31.6) | 8.0 (6.0, 16.1) | |||
Post-operative | 17.8 (7.1, 29.8) | 12.1 (6.9, 21.9) | |||
24 h post-operative | 26.8 (10.1, 34) | 16.1 (3.7, 36.8) | |||
TEG-PM AA MA (mm) | Pre-operative | 56.6 (52.1, 60.4) | <0.005 | 44.9 (23.3, 63.1) | 0.82 |
Intra-operative | 42.1 (30.4, 50.5) | 39.5 (11.5, 51.4) | |||
Post-operative | 39.1 (26.6, 48.6) | 39.2 (30.5, 50.3) | |||
24 h post-operative | 25.2 (14.2, 34) | 36.7 (12.5, 60) | |||
TEG-PM ADP percent inhibition | Pre-operative | 39 (16.6, 55.8) | <0.005 | 78.5 (39.4, 88.6) | 0.114 |
Intra-operative | 81.3 (59.1, 95) | 93 (72.8, 98.3) | |||
Post-operative | 85 (53, 99.1) | 94.1 (82.2, 100) | |||
24 h post-operative | 69.8 (57.2, 98.6) | 85.7 (40.9, 100) | |||
TEG-PM AA percent inhibition | Pre-operative | 12 (3.6, 21.9) | 0.006 | 16.1 (11, 48.4) | 0.08 |
Intra-operative | 26.7 (15.8, 48.6) | 39.8 (25.7, 65.3) | |||
Post-operative | 32 (17.4, 54.5) | 43.5 (32.6, 66.6) | |||
24 h post-operative | 69.8 (25.7, 88.9) | 52.7 (16, 90.2) | |||
MEIA ADP (AUC) | Pre-operative | 45 (33, 57.75) | 0.006 | 48 (34, 54) | 0.006 |
Intra-operative | 17.5 (10.3, 37.8) | 16 (11, 26) | |||
Post-operative | 35.5 (24.3, 53.3) | 29 (16, 32) | |||
24 h post-operative | 37.5 (26.3, 58) | 36 (31, 41) | |||
MEIA AA (AUC) | Pre-operative | 59 (41, 68.5) | <0.005 | 45 (32, 74) | 0.05 |
Intra-operative | 19.5 (11.3, 37.3) | 20 (15, 34) | |||
Post-operative | 38 (30.5, 49.8) | 31 (27, 58) | |||
24 h post-operative | 23.5 (17, 34.5) | 26 (21, 39) |
CPB, cardiopulmonary bypass; TEG-PM, thromboelastography with platelet mapping; ADP, adenosine diphosphate receptor; AA, arachidonic acid receptor; MEIA, multiple electrode impedance aggregometry; AUC, area under the curve.