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. Author manuscript; available in PMC: 2020 Apr 15.
Published in final edited form as: Comput Methods Appl Mech Eng. 2019 Jan 7;347:533–567. doi: 10.1016/j.cma.2018.12.008

Table 2.

Summary of the parameters for the generation of the synthetic test cases and the inversion. We report values for the following parameters: Ni , i = 1, 2, 3 denotes the grid size used for the discretization of the problem; ρw and ρg are the characteristic reaction factors for white and gray matter, ρ f is the overall reaction scaling factor; kw and kg are the characteristic diffusion parameters for white and gray matter, k f the overall scaling parameter for the isotropic part of the inhomogeneous diffusion coefficient for net migration of cancerous cells into surrounding tissue; n p is the number of Gaussian basis functions used for the parametrization of the tumor initial condition, σ is the standard deviation of the associated Gaussian basis functions, and maxiti = (maxiti,N , maxiti,K ) denotes the maximum number of Newton iterations and Krylov iterations (for the KKT system) for the tumor inversion (i = T ) and registration (i = R), respectively,.

SIN ATAV-REAC ATAV-DIF ATAV-LD RTRV
Ni {64, 128, 256} 128 128 128 256
ρw 1 1 1 1 1
ρg 0 0 0 0 0.2
ρ f 15 15 {5, 10, 15} {5, 10, 15} {0, 5, 10, 15}
kw 1 1 1 1 1
kg 0 0 0 0 0.1
k f 0 0 {0, 1E−2} {1E−2, 1E−1} {0,1E−2}
n p {8, 64, 512} 125 125 8 {125, 343}
σ π/10 π/10 π/10 π/15 Auto
maxitT (100, 100) (50, 100) (30, 60) (30, 60) (30, 30)
maxitR (100, 100) (50, 80) (50, 80) (50, 80) (10, 20)