Table 5.
Comparison of factors predicting outcome of FG with present study
| Author | No. of patients studied | Mortality rate (%) | Parameters predicting outcome |
|---|---|---|---|
| Clayton et al.[4] | 57 | 17.5 | BUN>50 mg/dL |
| Laor et al.[12] | 30 | 43 | FGSI>9 |
| Ruiz-Tovar et al.[14] | 70 | 22.9 | Ethylism, coexistence of neoplasms, presence of skin necrosis, myonecrosis, abdominal wall affection, number of debrided areas, re-operations serum creatinine >1.4 mg/dL Hb<10 g/dL PLC<150×109/L |
| Kara et al.[16] | 15 | 20 | RBS>140 mg/dL, the existence of septic shock on admission, spread of gangrene to the perineum and abdominal wall, BSA>24 cm2, cutaneous source of infection FGSI>7 |
| Janane et al.[20] | 70 | 11.4 | Extent of BSA involved |
| Altarac et al.[21] | 41 | 36.6 | Elevated HR and RR, high serum creatinine, low serum bicarbonate, CKD, higher median BSA affected Severe sepsis on admission SBP<90 mmHg FGSI >11 |
| Tuncel et al.[22] | 50 | 14 | Low Hb, high BUN, low albumin levels |
| Present study | 72 | 8.3 | Advanced age, DM, CKD, raised TLC-altered sensorium, shock at presentation, high FGSI/ACCI scores, deranged INR |
BMI: body mass index; DM: diabetes mellitus; Hb: hemoglobin; TLC: total leukocyte count; RBS: random blood sugar; FGSI: Fournier’s gangrene severity index; ACCI: age-adjusted Charlson Comorbidity Index; INR: international normalized ratio; HR: heart rate; RR: respiratory rate; CKD: chronic kidney disease; BSA: body surface area; BUN: blood urea nitrogen; SBP: systolic blood pressure; PLC: platlet count