TABLE 1. Demographic, clinical, and programmatic characteristics of smear-positive pulmonary tuberculosis (PTB) patients, Suriname, 2010 – 2015.
Characteristic |
Total (n = 469) |
% |
Cases (n = 59) |
% |
Controls (n = 410) |
% |
P value |
---|---|---|---|---|---|---|---|
Sex | |||||||
Male |
349 |
74.4 |
47 |
79.7 |
302 |
73.7 |
0.323a |
Female |
120 |
25.6 |
12 |
20.3 |
108 |
26.3 |
|
Age (years) | |||||||
Median |
42 |
|
43 (37 – 54) |
|
42 (31 – 51) |
|
0.126a |
Age groups (years) | |||||||
15-34 |
158 |
33.7 |
12 |
20.3 |
146 |
35.6 |
0.036a |
35-54 |
240 |
51.2 |
39 |
66.1 |
201 |
49.0 |
|
55+ |
71 |
15.1 |
8 |
13.6 |
63 |
15.4 |
|
HIV status | |||||||
Negative |
371 |
79.1 |
45 |
76.3 |
326 |
79.5 |
0.413b |
Positive |
87 |
18.6 |
11 |
18.6 |
76 |
18.5 |
|
Unknown |
11 |
2.3 |
3 |
5.1 |
8 |
2.0 |
|
Receiving ART | |||||||
Yes |
66 |
75.9 |
10 |
90.9 |
56 |
73.7 |
0.241b |
No |
13 |
14.9 |
1 |
9.1 |
12 |
15.8 |
|
Unknown |
8 |
9.2 |
0 |
0.0 |
8 |
10.5 |
|
DOT | |||||||
Yes |
309 |
65.9 |
41 |
69.5 |
268 |
65.4 |
0.532a |
No |
160 |
34.1 |
18 |
30.5 |
142 |
34.6 |
|
Hospitalization | |||||||
Yes |
417 |
88.9 |
53 |
89.8 |
364 |
88.8 |
0.898b |
No |
15 |
3.2 |
2 |
3.4 |
13 |
3.2 |
|
Unknown |
37 |
7.9 |
4 |
6.8 |
33 |
8.1 |
|
Hospitalization (days) | |||||||
Median (IQR) |
48 (30 – 71) |
|
93 (54 – 132) |
|
45 (29 – 66) |
|
< 0.001c |
Case type | |||||||
New |
430 |
91.7 |
53 |
89.8 |
377 |
92.0 |
|
Retreatment |
39 |
8.3 |
6 |
10.2 |
33 |
8.0 |
0.612d |
Diabetes Mellitus | |||||||
Yes |
65 |
13.9 |
5 |
8.5 |
60 |
14.6 |
0.200a |
No |
404 |
86.1 |
54 |
91.5 |
350 |
85.4 |
|
Bacillary load | |||||||
≤1+ |
196 |
41.8 |
15 |
25.4 |
181 |
44.1 |
0.015a |
2+ |
103 |
22.0 |
14 |
23.7 |
89 |
21.7 |
|
3+ |
170 |
36.2 |
30 |
50.8 |
140 |
34.1 |
|
Time to start TB treatment (days) | |||||||
Median (IQR) |
3 (0 – 8) |
|
1 (0 – 5) |
|
4 |
|
0.015c |
Rifampicin sensitivitye | |||||||
Resistant |
27 |
5.8 |
4 |
6.8 |
23 |
5.6 |
0.398b |
Sensitive |
237 |
50.5 |
34 |
57.6 |
203 |
49.5 |
|
Unknown |
205 |
43.7 |
21 |
35.6 |
184 |
44.9 |
|
Note: HIV = Human Immunodeficiency Virus; ART = Antiretroviral Therapy; IQR = interquartile range; DOT = Directly Observed Treatment. Other risk factors included smoking, alcohol, homelessness, prison, and drug use. Hospitalization was defined as a stay of 14 days or more.
a Chi-square test.
b Likelihood ratio.
c Mann-Whitney U test.
d Values from Fisher’s exact test were used.
e Rifampicin sensitivity was only available for cases after Xpert was implemented in 2012.
Source: Prepared by the authors from the study results, based on data from the National Tuberculosis Program database, Ministry of Health, Paramaribo, Suriname, 2019.