Table 5. Binary logistic regression analysis for predicting pregnancy using a cutoff value of 0.02 for caspase-3 levels.
| Coefficient | β | Std Deviation (S.E.) |
Wald | df | Significance (p) | eβ |
|---|---|---|---|---|---|---|
| Caspase-3 cutoff level 0.02 | -2.398 | 1.158 | 4.288 | 1 | 0.038 | 0.091 |
| Constant | 2.716 | 1.410 | 3.710 | 1 | 0.054 | 15.125 |
| Observed | Predicted pregnancy | % correct | ||||
| no | yes | |||||
| Pregnant after transfer | no | 8 | 8 | 50.0 | ||
| yes | 1 | 11 | 91.7 | |||
| Overall % correct | 67.9 | |||||
Relative levels of caspase-3 were detected in culture media from embryos cultured until day 2. The cutoff value was based on the results from the receiver-operating characteristics curve (Fig 5). The probability of predicting pregnancy at a caspase-3 cutoff level of 0.02 was 67.9% (p ≤ 0.05).