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. 2019 Dec 19;14(12):e0226651. doi: 10.1371/journal.pone.0226651

Fig 1. Langerhans cells but not dendritic cells are more susceptible to T/F viruses.

Fig 1

(A-B) Infection of (A) activated LCs and (B) moDCs by T/F-viruses and NL4.3Bal. (C) Ex vivo tissue explant was infected by different T/F viruses and NL4.3Bal and infection of emigrated LCs was measured. (D) Infection of vaginal immature LCs by different T/F-viruses and NL4.3Bal. The viral titers were normalized based on TCID50 measurements. Each dot represents the average percentage of infection per donor. Error bars are the mean ± SD of A, n = 5; B, n = 10; C, n = 5; D, n = 3 donors. LC: Langerhans cell, moDC: monocyte-derived dendritic cell, T/F: Transmitted Founder.