Skip to main content
. 2019 Dec 19;14(12):e0226821. doi: 10.1371/journal.pone.0226821

Fig 2. Association between HFE expression and HFE genotype or sex in TCGA lung cancer data.

Fig 2

(A) HFE gene expression based on HFE genotype (WT, H63D, C282Y, H63D and C282Y) in male primary tumor LUAD patients. (B) HFE gene expression based on HFE genotype (WT, H63D, C282Y, H63D and C282Y) in female primary tumor LUAD patients. (C) HFE gene expression based on HFE genotype (WT, H63D, C282Y, H63D and C282Y) in male primary tumor LUSC patients. (D) HFE gene expression based on HFE genotype (WT, H63D, C282Y, H63D and C282Y) in female primary tumor LUSC patients. Kruskal p = the p-value for the Kruskal-Wallis test comparing the median HFE expression levels in each of the four groups, Wilcox p1 = the p-value for the Wilcoxon rank sum test comparing the median HFE expression levels in WT HFE vs. H63D HFE, Wilcox p2 = the p-value for the Wilcoxon rank sum test comparing the median HFE expression levels in WT HFE vs. C282Y HFE, Wilcox p3 = the p-value for the Wilcoxon rank sum test comparing the median HFE expression levels in WT HFE vs. H63D/C282Y HFE.