Table 3. Deaths organized by underlying cause of death and by HCV serological status.
General Cause of Death | HCV+* | HCV-** | HR adjusted# | CI 95% | p-Value |
---|---|---|---|---|---|
N = 2,652 | N = 5,782 | ||||
All liver related deaths | 75 | 6 | 24.06 | (10.45–55.39) | <0.001 |
HCV | 23 | 0 | ∞ | - | - |
Other viral hepatitis infection | 4 | 1 | 7.10 | (0.78–64.52) | 0.082 |
Liver Disease | 30 | 4 | 15.22 | (5.34–43.37) | <0.001 |
Liver Cancer | 18 | 1 | 29.52 | (3.93–221.73) | 0.001 |
Non-Hepatic Cancer | 28 | 48 | 1.00 | (0.62–1.60) | 0.992 |
Cardiovascular-Related Causes | 17 | 29 | 1.03 | (0.56–1.88) | 0.931 |
Pulmonary Causes | 9 | 8 | 2.32 | (0.89–6.06) | 0.086 |
Trauma/Suicide | 32 | 45 | 1.66 | (1.05–2.61) | 0.029 |
Trauma | 32 | 40 | 1.86 | (1.17–2.97) | 0.009 |
Suicide | 0 | 5 | ∞ | - | - |
Drugs/Alcohol | 2 | 0 | ∞ | - | - |
Neurological Diseases | 7 | 13 | 0.90 | (0.36–2.28) | 0.830 |
Infection | 20 | 14 | 2.75 | (1.38–5.47) | 0.004 |
Other/Unknown | 19 | 27 | 1.39 | (0.77–2.52) | 0.277 |
Kidney Diseases | 3 | 4 | 1.26 | (0.28–5.72) | 0.761 |
Diabetes Mellitus | 1 | 5 | 0.33 | (0.38–2.87) | 0.315 |
Other | 15 | 18 | 1.74 | (0.87–3.47) | 0.117 |
All Deaths | 209 | 190 | 2.15 | (1.76–2.62) | <0.001 |
* HCV +: HCV seropositive only.
** HCV-: Seronegative for all infections tested.
#HR: HazardRatio adjusted by sex, age. Type of donation and type of donor dropped from final adjusted models. Male sex and increasing age acted as positive confounders on both adjusted models. CI: Confidence Interval