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. 2018 May 14;13(1):87–96. doi: 10.1111/1751-7915.13279

Figure 7.

Figure 7

The effect of Mab 4E4 on survival of Balb/c mice against PAO1 infection. (A) The effect of different dosages of Mab 4E4 on mice survival rate. Three dosages of Mab 4E4 (50 μg, 200 μg and 2 mg) were injected into mice (n = 10 per group) by i.v., respectively, at 2 h before bacterial infection (1.5e6 CFU). (B) The effect of different time points of Mab 4E4 (2 mg per mouse) injection on mice (n = 10 per group) survival rate. Mice were injected with Mab 4E4 2 h before, 2 h later or at the same time with PAO1 challenge (1.5e6 CFU). (C) The effect of Mab 4E4 delivery ways (i.v.; i.t.; i.p.) of Mab 4E4 on mice (n = 10 per group) survival rate. (D) The effect of Mab 4E4 on mouse survival against PAO1 infection compared with control IgG. Data are average ± SD and were analysed by using Prism7 GraphPadby. Data are representative of three independent experiments.