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. 2019 Dec 13;10:879. doi: 10.3389/fendo.2019.00879

Table 2.

miRNAs and their validated target genes related with insulin sensitivity obtained using miRTarBase.

miRNA miRBase ID Validated target genes
miR-146a hsa-miR-146a-5p CFH, TLR2, FADD, TRAF6, IRAK1, BRCA2, BRCA1, FAF1, PA2G4, NFKB1, EGFR, FAS, ERBB4, SMAD4, TLR4, STAT1, ICAM1, SMAD2, PTGS2, CCL5, PTGES2, CXCL12, RAC1, COX2, SOS1, NOTCH2, SOX2, IL6, RHOA, LFNG, TGFB1, MIF, NOTCH1, CCND2, CCND1, RHO, RARB, NOS1
miR-155 hsa-miR-155-5p MECP2, SOCS1, SHIP1, DET1, SMAD5, HIVEP2, JARID2, RHEB, PKN2, MYO10, RHOA, FOXO3, RUNX2, KBTBD2, KRAS, CYR61, SMAD2, SOX6, JUN, KDM3A, IL13RA1, BCL6, CARHSP1, MYBL1, NKX3-1, PRKAR1A, RAC1, ANXA2, CCND1, INPP5F, PAK2, UBQLN1, NFKB1, RAD51, MXI1, SOCS6, PTEN
miR-320 hsa-miR-320a-3p IGF1R, HOXA10, VDAC1, MYC, ITGB3, RAC1, PDCD4, BMI1, ARF4, NRP1, NFAT, PTEN, RAB14, FOXM1, RUNX2, VEGFA, NOD2, FH, AR, HMGB1
miR-370 hsa-miR-370-3p CPT1A, TGFBR2, FOXO1, LIN28A, SIK1, AQP3, CPT1B, FOXN3, HNRNPA1, IFNGR2, TRAF1, PYGO2, GPR146, PTEN, NUCKS1, WDTC1
miR-486 hsa-miR-486-5p CD40, ARHGAP5, OLFM4, PIM1, IGF1R, CADM1, PCCA, FOXP1, SEC23IP, MACROD2, ARF6, FBN1, CDK4, SMAD2, FOXO1, PTEN, PIK3R1, HMGA1